Synthesis of Some New Heterocyclic Compounds with Potential Biological Activity

Authors: not saved
Abstract:

A series of new 2-arylimino-3-aryl-5-[5?-(3,4-dichlorophenyl)-2?-furylidene]-4-thiazolidinones (3a-l) have been synthesised by the condensation of 5-(3,4-dichlorophenyl)-2-furaldehyde 1 with 2-arylimino-3-aryl-5H-4-thiazolidinones 2 in glacial acetic acid. The physical and spectral data of the synthesised compounds are determined. The synthesised compounds have been screened for their in vitro antimicrobial activity against various strains of bacteria and fungi.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

synthesis of some new heterocyclic compounds with potential biological activity

a series of new 2-arylimino-3-aryl-5-[5?-(3,4-dichlorophenyl)-2?-furylidene]-4-thiazolidinones (3a-l) have been synthesised by the condensation of 5-(3,4-dichlorophenyl)-2-furaldehyde 1 with 2-arylimino-3-aryl-5h-4-thiazolidinones 2 in glacial acetic acid. the physical and spectral data of the synthesised compounds are determined. the synthesised compounds have been screened for their in vitro ...

full text

detection of volatile compounds of medicinal plants with some nano-sorbents using modified or new methodologies and investigation of antioxidant activity of their methanolic extracts

in this work, a novel and fast method for direct analysis of volatile compounds (davc) of medicinal plants has been developed by holding a filament from different parts of a plant in the gc injection port. the extraction and analysis of volatile components of a small amount of plant were carried out in one-step without any sample preparation. after optimization of temperature, extraction time a...

Synthesis, reactions and biological activity of some new bis-heterocyclic ring compounds containing sulphur atom

BACKGROUND The derivatives of thieno[2,3-b]thiophene belong to a significant category of heterocyclic compounds, which have shown a wide spectrum of medical and industrial application. RESULTS A new building block with two electrophilic center of thieno[2,3-b]thiophene derivatives 2 has been reported by one-pot reaction of diketone derivative 1 with Br2/AcOH in excellent yield. A variety of h...

full text

Tandem Reactions Using Nitrile Imines: Synthesis of Some Novel Heterocyclic Compounds with Expected Biological Activity

New functionalized 7,9-dimethylpyrimido[4,5-d][1,2,4]triazolo[4,3-a]pyrimidine5,6,8(1H,7H,9H)-trione derivatives were synthesized via reaction of the hydrazonoyl halides with 7,8-dihydro-1,3-dimethyl-7-thioxopyrimido[4,5-d]pyrimidine-2,4,5(1H,3H,6H)trione. The biological activity of the products has been evaluated. The mechanism and the regioselectivity of the studied reactions have been discus...

full text

Synthesis and Modification of some Heterocyclic Compounds with Potential Biological Activity Coupled on Poly (Maleic Anhydride – Methyl Methacrylate)

This paper presents some results concerning the immobilization through chemical bonds of some biologically active compounds on the maleic anhydridemethyl methacrylate) copolymer. The high reactivity of the anhydride cycle of the polymer has allowed us to obtain conjugates in which the biologically active compounds of some heterocyclic compounds are immobilized on the polymeric support through a...

full text

Utility of azalactones in synthesis of some new heterocyclic compounds

Azalactone 1 can be synthesized via treatment of 4chlorobenzoyl glycine with p-anisaldehyde in the presence of acetic anhydride and sod Acetate. The behaviour of azalactone 1 towards nitrogen nucleophiles, for example, anthranilic acid, 6-aminopyrimidin-2,4-dione and 2-amino-6-phenyl 1,3,4thiadiazole can be investigated. Benzoxazone 2 can be treated with hydrazine hydrate, hydroxylamine hydroch...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 17  issue 4

pages  -

publication date 2006-12-01

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023